Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Dichloro-2-nitrobenzene → 2-(beta,gamma-Dihydroxypropyl)amino-6-chloronitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Dichloro-2-nitrobenzene | HCID 11759 | — |
| 반응물 | 3-Amino-1,2-propanediol | HCID 73561 | — |
| 용매 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 생성물 | 2-(beta,gamma-Dihydroxypropyl)amino-6-chloronitrobenzene | HCID 20035240 | — |
반응 단계
0.2 mole (38.4 g) of 2,6-dichloronitrobenzene and 0.6 mole (54.6 g) of 3-aminopropane-1,2-diol in 200 ml of 1-methyl-2-pyrrolidone are heated to 80° C. The reaction mixture is diluted with ice. The product expected precipitates. After recrystallizing from isopropanol, it melts at 126° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04845293 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-15b4c36b60604eb984e0b22c2aa363ea |
| 출처 메모 | uspto-grants-1989_07 |