Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-bromobutanimide → 1-(Bromomethyl)-2-chloro-4-fluorobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 2-Chloro-4-fluorotoluene | HCID 96747 | — |
| 촉매 | Benzoyl Peroxide | HCID 7187 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 1-(Bromomethyl)-2-chloro-4-fluorobenzene | HCID 2725062 | 75.5% |
반응 단계
By the method of Example 7, Step C, 141.4 g (0.978 mole) of 2-chloro-4-fluorotoluene, 175.8 g (0.978 mole) of N-bromosuccinimide, and 5.0 g of benzoyl peroxide in 15 liters of carbon tetrachloride were reacted, yielding 165 g of 2-chloro-4-fluorobenzyl bromide as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04846882 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-92bbe4b3fa884de7adea63d2004552e8 |
| 출처 메모 | uspto-grants-1989_07 |