Dichloromethane → 2-{4-[4-(2-Hydroxy-2-methylpropionyl)piperazin-1-yl]anilino}-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)-5-chloropyrimidine

반응식

[C:8]([n:9]1[cH:10][cH:11][n:12][cH:13]1)([n:14]1[cH:15][cH:16][n:17][cH:18]1)=[O:19].[Cl:49][CH2:50][Cl:51].[N:20]1([c:26]2[cH:27][cH:28][c:29]([NH:30][c:31]3[n:32][cH:33][c:34]([Cl:46])[c:35](-[c:37]4[cH:38][n:39][c:40]([CH3:45])[n:41]4[CH:42]([CH3:43])[CH3:44])[n:36]3)[cH:47][cH:48]2)[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]1.[OH:1][C:2]([C:3](=[O:4])[OH:5])([CH3:6])[CH3:7]>>[OH:1][C:2]([C:3](=[O:4])[N:23]1[CH2:22][CH2:21][N:20]([c:26]2[cH:27][cH:28][c:29]([NH:30][c:31]3[n:32][cH:33][c:34]([Cl:46])[c:35](-[c:37]4[cH:38][n:39][c:40]([CH3:45])[n:41]4[CH:42]([CH3:43])[CH3:44])[n:36]3)[cH:47][cH:48]2)[CH2:25][CH2:24]1)([CH3:6])[CH3:7]