4,6-Nonanedione → 2-Methyl-5,7-dipropylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
반응식
[NH2:1][C:2]1[NH:6][N:5]=[C:4]([CH3:7])[C:3]=1[C:8]#[N:9].[CH3:10][CH2:11][CH2:12][C:13](=O)[CH2:14][C:15](=O)[CH2:16][CH2:17][CH3:18]>C(O)(=O)C>[CH3:7][C:4]1[C:3]([C:8]#[N:9])=[C:2]2[N:1]=[C:13]([CH2:12][CH2:11][CH3:10])[CH:14]=[C:15]([CH2:16][CH2:17][CH3:18])[N:6]2[N:5]=1참가 물질
4
실험 절차
A stirred mixture of 4.88 g of 5-amino-3-methylpyrazole-4-carbonitrile and 6.25 g of 4,6-nonanedione in 50 ml of glacial acetic acid was heated at reflux for 10 hours. The reaction mixture after reflux was worked up as described in Example 50 to give 7.80 of 2-methyl-5,7-dipropylpyrazolo[1,5-a]pyrimidine-3-carbonitrile, mp 73°-74° C.
후처리
- temperaturewas heated
- temperatureat reflux for 10 hours
- temperatureThe reaction mixture after reflux
출처 및 근거
- ORD 기록
- ord-89c615348933471da2cd3e9a21c3df0d
- 출처 데이터셋
- uspto-grants-1989_07
- 특허 번호
- US04847256
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