Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N-Dimethylethylenediamine → N-[2-(dimethylamino)ethyl]-6-nitro-1H-indole-2-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N-Dimethylethylenediamine | HCID 66053 | — |
| 반응물 | Methyl 6-nitro-1H-indole-2-carboxylate | HCID 11816863 | — |
| 생성물 | N-[2-(dimethylamino)ethyl]-6-nitro-1H-indole-2-carboxamide | HCID 85801420 | 84% |
반응 단계
500 mg (2.27 mmole) 6-Nitro-1H-indole-2-carboxylic acid methyl ester was dissolved in 4 mL neat N1,N1-dimethyl-ethane-1,2-diamine, was kept at 55° C. overnight and was evaporated. The oily residue was triturated with n-hexane to give 528 mg (84%) yellow solid which was no further purified. MS: 277.13 (calcd for M+H+:277.13)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06849713B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-437bfcf42a734cadaba4bc4b65654239 |
| 출처 메모 | uspto-grants-2005_02 |