Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Difluorobenzene → 1,2-Difluorobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Difluorobenzene | HCID 9741 | — |
| 반응물 | Fluorobenzene | HCID 10008 | — |
| 반응물 | Fluorine | HCID 24524 | — |
| 생성물 | 1,2-Difluorobenzene | HCID 9706 | — |
| 생성물 | Fluorobenzene | HCID 10008 | — |
반응 단계
According to Sams et al, "Molecular Sieve Fluorination of Fluorobenzene Using Elemental Fluorine," J. Org. Chem. 43(11), 2273 (1978), attempts were made to prepare 1,3-difluorobenzene using a molecular sieve fluorination technique. Fluorination of monofluorobenzene resulted in the isolation of various isomers of difluorobenzene in 19% yield; the highest reported yield for the meta isomer was 1.2%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04847442 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-94ebc396e22e452ca94dedae374927e1 |
| 출처 메모 | uspto-grants-1989_07 |