Dimethylformamide → 3-Bromo-2-chloro-7-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine

반응식

[Br:1][c:2]1[cH:3][n:4][c:5]2[n:6]1[CH2:7][CH2:8][N:9]([C:11](=[O:12])[c:13]1[c:14]([Cl:23])[c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][cH:17][cH:18]1)[CH2:10]2.[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[Cl:24][N:25]1[C:26](=[O:27])[CH2:28][CH2:29][C:30]1=[O:31]>>[Br:1][c:2]1[c:3]([Cl:24])[n:4][c:5]2[n:6]1[CH2:7][CH2:8][N:9]([C:11](=[O:12])[c:13]1[c:14]([Cl:23])[c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][cH:17][cH:18]1)[CH2:10]2

참가 물질

반응물 3

HCID 6228Dimethylformamide

HCID 31398Chlorosuccinimide

HCID 497852023-Bromo-7-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine

생성물 1

HCID 497853733-Bromo-2-chloro-7-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine

출처 및 근거

ORD 기록: ord-1def49753ea947348f3748d5f972154b
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

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