1-Boc-2-Isopropylpiperazine → Tert-butyl 4-[(2-chloro-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-2-propan-2-ylpiperazine-1-carboxylate

반응식

[C:32]([CH3:33])([CH3:34])([CH3:35])[O:36][C:37](=[O:38])[N:39]1[CH:40]([CH:45]([CH3:46])[CH3:47])[CH2:41][NH:42][CH2:43][CH2:44]1.[Cl:1][c:2]1[n:3][c:4]([N:26]2[CH2:27][CH2:28][O:29][CH2:30][CH2:31]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][N:15]([C:16]([CH3:17])([CH3:18])[C:19]([N:20]([CH3:21])[CH3:22])=[O:23])[CH2:24][CH2:25]1)[s:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:26]2[CH2:27][CH2:28][O:29][CH2:30][CH2:31]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:42]1[CH2:41][CH:40]([CH:45]([CH3:46])[CH3:47])[N:39]([C:37]([O:36][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:38])[CH2:44][CH2:43]1)[s:10]2

참가 물질

반응물 2

HCID 441187971-Boc-2-Isopropylpiperazine

HCID 591512572-[4-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperazin-1-yl]-N,N-dimethyl-isobutyramide

생성물 1

HCID 72541734Tert-butyl 4-[(2-chloro-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-2-propan-2-ylpiperazine-1-carboxylate

출처 및 근거

ORD 기록: ord-889976d6557f4b9697a80d05f120ecbc
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

반응 노트

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