Thionyl Chloride → 2,2,5,5-Tetramethylcyclopentanecarbonyl chloride

HRID 231729노트

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HRID 231729 반응식
[CH3:1][C:2]1([CH3:12])[CH2:6][CH2:5][C:4]([CH3:8])([CH3:7])[CH:3]1[C:9](O)=[O:10].S(Cl)([Cl:15])=O>C1(C)C=CC=CC=1>[CH3:1][C:2]1([CH3:12])[CH2:6][CH2:5][C:4]([CH3:8])([CH3:7])[CH:3]1[C:9]([Cl:15])=[O:10]

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 10197889Cyclopentanecarboxylic acid, 2,2,5,5-tetramethyl-

생성물 1

HCID 139066402,2,5,5-Tetramethylcyclopentanecarbonyl chloride수율 69%

시약·촉매·용매 1

HCID 1140Toluene용매

반응 조건

온도
80 °C

실험 절차

2.51 g of 2,2,5,5-tetramethylcyclopentanecarboxylic acid was dissolved in 10 ml of toluene, and 2.5 ml of thionyl chloride was added thereto. The mixture was stirred at 80° C. for 3 hours. The reaction solution was concentrated and then distilled under reduced pressure, whereby 2.0 g of 2,2,5,5-tetramethylcyclopentanecarbonyl chloride was obtained. Yield 69%. (b.p. 110°-120° C./60 mmHg).

후처리

  1. concentrationThe reaction solution was concentrated
  2. distillationdistilled under reduced pressure

출처 및 근거

ORD 기록
ord-601deb541d284bfda9b0049aeab201e0
출처 데이터셋
uspto-grants-1989_07
특허 번호
US04847390

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