Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diazomethane → 2-(2,4-Dichlorobenzoyl)-2-(2,4-dichlorophenyl)oxirane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diazomethane | HCID 9550 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Urea, (nitrosomethyl)- | HCID 104823 | — |
| 반응물 | 1,2-Bis(2,4-dichlorophenyl)ethane-1,2-dione | HCID 13391683 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 2-(2,4-Dichlorobenzoyl)-2-(2,4-dichlorophenyl)oxirane | HCID 19870083 | — |
반응 단계
With cooling and stirring, an ethereal diazomethane solution prepared from 3.1 g of nitrosomethylurea and aqueous sodium hydroxide solution in ether is added dropwise to a solution of 3.4 g of 2,2',4,4'-tetrachlorobenzil in 50 ml of dioxane. When the dropwise addition is complete, stirring is continued for 16 hours at room temperature, and the reaction mixture is then concentrated to dryness. The residual oil is crude 2-(2,4-dichlorobenzoyl)-2-(2,4-dichlorophenyl)oxirane which is purified by high vacuum distillation.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04849007 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-068a47997e2c45ea9953c3a15c70f647 |
| 출처 메모 | uspto-grants-1989_07 |