Nitric Acid → 1,3-Dichloro-4,6-dinitrobenzene

HRID 231755노트

반응식

HRID 231755 반응식
[N+:1]([O-:4])([OH:3])=O.[Cl:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-:14])=[O:13])=[C:8]([Cl:15])[CH:7]=1>OS(O)(=O)=O>[Cl:5][C:6]1[C:11]([N+:1]([O-:4])=[O:3])=[CH:10][C:9]([N+:12]([O-:14])=[O:13])=[C:8]([Cl:15])[CH:7]=1

참가 물질

4

반응물 2

HCID 944Nitric AcidHCID 118992,4-Dichloronitrobenzene

생성물 1

HCID 772861,3-Dichloro-4,6-dinitrobenzene수율 76.8%

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매2회

실험 절차

Ml. 11.3 of fuming nitric acid (0.275 mole) in 96% H2SO4 (50 ml) was dropwise added under stirring at room temperature to 48 g of 1,3-dichloro-4-nitrobenzene (0.25 mole) in 96% H2SO4 (350 ml). The mixture was stirred for two hours, then poured into crushed ice. The separated solid was washed with cold water to neutrality, dried under vacuum and crystallized from ethanol (170 ml) to give the dinitro compound (A), 45.5 g, yield 76.8%, as yellow prisms.

후처리

  1. additionpoured
  2. custominto crushed ice
  3. washThe separated solid was washed with cold water to neutrality
  4. customdried under vacuum
  5. customcrystallized from ethanol (170 ml)

출처 및 근거

ORD 기록
ord-a4b5d642109249b797db5a62ca7b94b1
출처 데이터셋
uspto-grants-1989_07
특허 번호
US04849327

반응 노트

불러오는 중…