Pyrazole → 4-Ethoxy-6-methyl-2-(1H-pyrazol-1-yl)pyrimidine
반응식
Cl[C:2]1[N:7]=[C:6]([O:8][CH2:9][CH3:10])[CH:5]=[C:4]([CH3:11])[N:3]=1.[NH:12]1[CH:16]=[CH:15][CH:14]=[N:13]1>O1CCCC1>[CH2:9]([O:8][C:6]1[CH:5]=[C:4]([CH3:11])[N:3]=[C:2]([N:12]2[CH:16]=[CH:15][CH:14]=[N:13]2)[N:7]=1)[CH3:10]참가 물질
4
실험 절차
In anhydrous tetrahydrofuran, 173 mg of 2-chloro-4-ethoxy-6-methylpyrimidine was substituted with 68 mg of pyrazole. The reaction mixture was treated according to the procedure of Example 5 to yield 110 mg of 4-ethoxy-6-methyl-2-(1-pyrazolyl)pyrimidine, an oily compound.
후처리
- additionThe reaction mixture was treated
출처 및 근거
- ORD 기록
- ord-330ada8d1abb4716b034f2bc401fae4a
- 출처 데이터셋
- uspto-grants-1989_07
- 특허 번호
- US04849424
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