Dimethylamine → HCID 22182618, 화합물

HRID 23181노트

반응식

HRID 23181 반응식
Cl[C:2]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[C:9](=[O:10])[O:8][CH2:7]2)=[O:3].[CH3:14][NH:15][CH3:16]>C1COCC1>[CH3:14][N:15]([CH3:16])[C:2]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[C:9](=[O:10])[O:8][CH2:7]2)=[O:3]

참가 물질

4

반응물 2

HCID 674DimethylamineHCID 98155555-Chlorocarbonylphthalide

생성물 1

HCID 22182618HCID 22182618, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

A solution of 5-chlorocarbonylphthalid (32 g, 0.16 mole) in THF (300 ml) is added to dimethylamine (40% v/v in water, 300 ml) and ice (100 g). The mixture is stirred for 1 hour. THF is evaporated off in vacuo and precipitated crystals are filtred off at 5° C. and washed with water (100 ml).

후처리

  1. customTHF is evaporated off in vacuo
  2. customprecipitated crystals
  3. customare filtred off at 5° C.
  4. washwashed with water (100 ml)

출처 및 근거

ORD 기록
ord-877b7f1505ba404c8c115a7ea44af5ed
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06849749B2

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