1-(2-Bromoacetyl)pyrrolidine-2-carbonitrile → 1-[2-[[4-(Hydroxymethyl)-1-bicyclo[2.2.2]octanyl]amino]acetyl]pyrrolidine-2-carbonitrile

반응식

[Br:12][CH2:13][C:14](=[O:15])[N:16]1[CH:17]([C:21]#[N:22])[CH2:18][CH2:19][CH2:20]1.[NH2:1][C:2]12[CH2:3][CH2:4][C:5]([CH2:10][OH:11])([CH2:6][CH2:7]1)[CH2:8][CH2:9]2>>[NH:1]([C:2]12[CH2:3][CH2:4][C:5]([CH2:10][OH:11])([CH2:6][CH2:7]1)[CH2:8][CH2:9]2)[CH2:13][C:14](=[O:15])[N:16]1[CH:17]([C:21]#[N:22])[CH2:18][CH2:19][CH2:20]1

참가 물질

반응물 2

HCID 178609191-(2-Bromoacetyl)pyrrolidine-2-carbonitrile

HCID 23152950{4-Aminobicyclo[2.2.2]octan-1-yl}methanol

생성물 1

HCID 231529531-[2-[[4-(Hydroxymethyl)-1-bicyclo[2.2.2]octanyl]amino]acetyl]pyrrolidine-2-carbonitrile

출처 및 근거

ORD 기록: ord-8ac0fa5e9a1748dcbefa19c8e724846a
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…