Dichloromethane → 3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-(3-oxo-[1,4,2]dioxazinan-2-ylmethyl)-benzamide

HRID 2321418

반응식

[CH2:34]1[CH2:36][CH2:35][CH2:37][O:38]1.[Cl:31][CH2:32][Cl:33].[F:1][c:2]1[c:3]([NH:22][c:23]2[c:24]([F:30])[cH:25][c:26]([I:29])[cH:27][cH:28]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH2:16][NH:17][O:18][CH2:19][CH2:20][OH:21])[c:14]1[F:15]>>[F:1][c:2]1[c:3]([NH:22][c:23]2[c:24]([F:30])[cH:25][c:26]([I:29])[cH:27][cH:28]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH2:16][N:17]2[O:18][CH2:19][CH2:20][O:21][C:37]2=[O:38])[c:14]1[F:15]

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 8028Tetrahydrofuran

HCID 115774573,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-[(2-hydroxy-ethoxyamino)-methyl]-benzamide

생성물 1

HCID 116138803,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-(3-oxo-[1,4,2]dioxazinan-2-ylmethyl)-benzamide

출처 및 근거

ORD 기록: ord-3855da204cfe4feb9466f4e73e11f188
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

연결된 노트

불러오는 중…