Thionyl Chloride → HCID 14049831, 화합물

HRID 232202노트

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HRID 232202 반응식
O=[C:2]([CH2:16][CH2:17][C:18]([O-:20])=[O:19])[C:3]([O:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][CH:8]=1)=[O:4].S(Cl)([Cl:23])=O>ClCCCl>[Cl:23][C:2]1([C:3]([O:5][CH2:6][C:7]2[CH:8]=[CH:9][C:10]([N+:13]([O-:15])=[O:14])=[CH:11][CH:12]=2)=[O:4])[CH2:16][CH2:17][C:18](=[O:19])[O:20]1

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 221664155-[(4-Nitrophenyl)methoxy]-4,5-dioxopentanoate

생성물 1

HCID 14049831HCID 14049831, 화합물

시약·촉매·용매 1

HCID 111,2-Dichloroethane용매

실험 절차

In 16 ml of 1,2-dichloroethane was dissolved 0.40 g of the Compound (1) obtained in Example 1. To the solution was added 0.88 ml of thionyl chloride. The mixture was heated for 10 hours under reflux. The solvent was evaporated off, and the residue was subjected to a silica gel column chromatography, followed by elution with hexane-ethyl acetate (3:1) to give 0.36 g of the subject Compound (15) as colorless oil.

후처리

  1. temperatureThe mixture was heated for 10 hours
  2. temperatureunder reflux
  3. customThe solvent was evaporated off
  4. washfollowed by elution with hexane-ethyl acetate (3:1)

출처 및 근거

ORD 기록
ord-d0ae1d9eed84417eaaa8d23cb6753991
출처 데이터셋
uspto-grants-1989_07
특허 번호
US04851422

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