Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-Oxocycloheptane-1-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-Cyclohepten-1-one | HCID 70723 | — |
| 반응물 | Diethyl aluminum cyanide | HCID 16686413 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 3-Oxocycloheptane-1-carbonitrile | HCID 15702746 | — |
반응 단계
To 100 mL of toluene add 2-cyclohepten-1-one (11.0 g, 0.1 mol) and 200 mL (1M solution in toluene, 0.2 mol) of diethylaluminum cyanide. Monitor the reaction by thin-layer chromatography. Upon completion add 1M aqueous HCl until gas evolution ceases. Extract twice with 100 mL of ether. Dry the organic phase with Na2SO4. Filter off the drying agent and evaporate the solvent in vacuo to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04851526 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-e95315393a654245bf2d5423cbf03910 |
| 출처 메모 | uspto-grants-1989_07 |