3-Hydroxyazetidine → 1-[2-(3,4-Dimethoxyphenyl)ethyl]azetidin-3-ol

HRID 232306노트

반응식

HRID 232306 반응식
[NH:1]1[CH2:4][CH:3]([OH:5])[CH2:2]1.Br[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([O:17][CH3:18])[CH:10]=1>>[CH3:18][O:17][C:11]1[CH:10]=[C:9]([CH2:8][CH2:7][N:1]2[CH2:4][CH:3]([OH:5])[CH2:2]2)[CH:14]=[CH:13][C:12]=1[O:15][CH3:16]

참가 물질

3

반응물 2

HCID 15142903-HydroxyazetidineHCID 114706023,4-Dimethoxyphenethyl bromide

생성물 1

HCID 200313801-[2-(3,4-Dimethoxyphenyl)ethyl]azetidin-3-ol

실험 절차

In a manner similar to Preparation 73, react azetidin-3-ol with 1-bromo-2-(3,4-dimethoxyphenyl)ethane to obtain the title compound.

후처리

  1. customIn a manner similar to Preparation 73

출처 및 근거

ORD 기록
ord-f581dcc50077449698ee1eba14ab64fe
출처 데이터셋
uspto-grants-1989_07
특허 번호
US04851526

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