Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromine → 2-Bromo-1-[4-(1H-imidazol-1-yl)phenyl]ethanone hydrobromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 1-(4-(1H-Imidazol-1-yl)phenyl)ethanone | HCID 82316 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Hydrogen Bromide | HCID 260 | — |
| 생성물 | 2-Bromo-1-[4-(1H-imidazol-1-yl)phenyl]ethanone hydrobromide | HCID 20031310 | — |
반응 단계
Add bromine (5.71 mL, 0.111 mol) to a solution of 4'-(1H-imidazol-1-yl)acetophenone (20.75 g, 0.111 mol) in 30-32% HBr in acetic acid. Stir the mixture overnight and collect the crystals. Wash the crystals with ethanol (3×50 mL) and air dry for 2h at room temperature to afford the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04851526 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-27f1074a998940f2a6cf78bb3d89b3ee |
| 출처 메모 | uspto-grants-1989_07 |