Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-[2-(4-Methylphenoxy)ethyl]acetamide → N-Ethyl-2-(4-methylphenoxy)ethanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-[2-(4-Methylphenoxy)ethyl]acetamide | HCID 538338 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | N-Ethyl-2-(4-methylphenoxy)ethanamine | HCID 20031351 | — |
반응 단계
To a chilled suspension of 0.49 g (013 mol) lithium aluminium hydride in 50 mL anhydrous ether, add 5.0 g (025 mol) N-[2-(4-methylphenoxy)ethyl]acetamide at a rate which maintains the reaction temperature below 10° C. Allow to warm to room temperature and stir at ambient temp. for 24 hrs. After this time, quench the mixture with H2O and filter the salts. Concentrate the filtrate to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04851526 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-936c3c50aef24950848ed4c0bb4bc33b |
| 출처 메모 | uspto-grants-1989_07 |