Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloroethanol → N-Ethyl-N-(2-hydroxyethyl)-N-[2-(4-methylphenoxy)ethyl]-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloroethanol | HCID 34 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | N-Ethyl-2-(4-methylphenoxy)ethanamine | HCID 20031351 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-Ethyl-N-(2-hydroxyethyl)-N-[2-(4-methylphenoxy)ethyl]-amine | HCID 20031320 | — |
반응 단계
Add 0.90 g (011 mol) 2-chloroethanol to a solution of 2.0 g (0.11 mol) N-ethyl-N-[2-(4-methylphenoxy)ethyl]amine and 1.7 g (012 mol) potassium carbonate in 50 mL methanol. Stir at room temperature for 24 hr. After this time, remove the solvents in vacuo and dissolve the residue in 25 mL water. Adjust the aqueous to pH=8 with 5% sodium bicarbonate solution and extract 3×50 mL methylene chloride. Dry the combined organics over sodium sulfate and evaporate the solvent to obtain the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04851526 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-f2eb8d7c4d324159a69739c911fcf09a |
| 출처 메모 | uspto-grants-1989_07 |