Imidazole → HCID 14555636, 화합물

HRID 232328노트

반응식

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][N:13]2[CH2:16][CH:15]([C:17]([C:19]3[CH:24]=[CH:23][C:22](F)=[CH:21][CH:20]=3)=[O:18])[CH2:14]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[NH:26]1[CH:30]=[CH:29][N:28]=[CH:27]1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][N:13]2[CH2:16][CH:15]([C:17]([C:19]3[CH:24]=[CH:23][C:22]([N:26]4[CH:30]=[CH:29][N:28]=[CH:27]4)=[CH:21][CH:20]=3)=[O:18])[CH2:14]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

참가 물질

반응물 2

HCID 795Imidazole

HCID 20031367HCID 20031367, 화합물

생성물 1

HCID 14555636HCID 14555636, 화합물

실험 절차

In a manner similar to Example 26, react [1-[2-(3,4-dimethoxyphenyl)ethyl]azetidin-3-yl](4-fluorophenyl)-methanone with 1H-imidazole to obtain the title compound.

출처 및 근거

ORD 기록: ord-31ec7bd54c5540839e226d3b96d3ccf8
출처 데이터셋: uspto-grants-1989_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04851526

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