Imidazole → HCID 20031304, 화합물

반응식

[CH:1]1([CH2:6][N:7]([CH2:22][CH:23]=[CH2:24])[CH:8]([CH3:21])[CH2:9][CH2:10][CH2:11][C:12]([C:14]2[CH:19]=[CH:18][C:17](F)=[CH:16][CH:15]=2)=[O:13])[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:25]1[CH:29]=[CH:28][N:27]=[CH:26]1>>[CH:1]1([CH2:6][N:7]([CH2:22][CH:23]=[CH2:24])[CH:8]([CH3:21])[CH2:9][CH2:10][CH2:11][C:12]([C:14]2[CH:19]=[CH:18][C:17]([N:25]3[CH:29]=[CH:28][N:27]=[CH:26]3)=[CH:16][CH:15]=2)=[O:13])[CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 795Imidazole

HCID 20031326HCID 20031326, 화합물

생성물 1

HCID 20031304HCID 20031304, 화합물

실험 절차

In a manner similar to Example 26, react 5-[(cyclopentylmethyl)(2-propenyl)amino]-1-(4-fluorophenyl)hexan-1-one with 1H-imidazole to obtain the title compound.

출처 및 근거

ORD 기록: ord-e32b97dbeb4243b2b8000603f975f091
출처 데이터셋: uspto-grants-1989_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04851526

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