2-Chloropyridine-4-boronic acid → 2-(2-Chloro-pyridin-4-yl)-4-methyl-6-(3-methyl-4-trifluoromethyl-phenyl)-pyrimidine

반응식

[Cl:1][c:2]1[n:3][c:4]([CH3:19])[cH:5][c:6](-[c:8]2[cH:9][c:10]([CH3:18])[c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)[n:7]1.[Cl:20][c:21]1[n:22][cH:23][cH:24][c:25]([B:27]([OH:28])[OH:29])[cH:26]1>>[c:2]1(-[c:25]2[cH:24][cH:23][n:22][c:21]([Cl:20])[cH:26]2)[n:3][c:4]([CH3:19])[cH:5][c:6](-[c:8]2[cH:9][c:10]([CH3:18])[c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)[n:7]1

참가 물질

반응물 2

HCID 51515952-Chloropyridine-4-boronic acid

HCID 574686572-Chloro-4-(3-methyl-4-trifluoromethyl-phenyl)-6-methyl-pyrimidine

생성물 1

HCID 574687692-(2-Chloro-pyridin-4-yl)-4-methyl-6-(3-methyl-4-trifluoromethyl-phenyl)-pyrimidine

출처 및 근거

ORD 기록: ord-b698191ad6c0422eb7f8fb00244a791a
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

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