Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5'-Azido-2',5'-dideoxy-5-n-propyluridine → 5'-Amino-2',5'-dideoxy-5-n-propyluridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5'-Azido-2',5'-dideoxy-5-n-propyluridine | HCID 53928131 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 5'-Amino-2',5'-dideoxy-5-n-propyluridine | HCID 53664810 | — |
반응 단계
0.38 g of 5'-azido-2',5'-dideoxy-5-n-propyluridine was dissolved in 100 ml of ethanol and the solution was hydrogenated in the presence of 0.1 g of 10% palladium-on-charcoal catalyst for 2 hours at room temperature and under atmospheric pressure. The catalyst was removed by filtration and the filtrate was evaporated to give 5'-amino-2',5'-dideoxy-5-n-propyluridine in the form of a solid which was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04851519 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-40bf434547f240a4a0ffda9ec3a66eb1 |
| 출처 메모 | uspto-grants-1989_07 |