Tetrahydrofuran → (r)-4-Phenyl-2-oxazolidinone tetra n-butylammonium salt

참여 물질

역할	이름	HCID	투입량
반응물	Tetrahydrofuran	HCID 8028	—
반응물	Sodium hydride	HCID 24758	—
반응물	(4R)-4-phenyl-1,3-oxazolidin-2-one	HCID 730425	—
촉매	Tetrabutylammonium Bromide	HCID 74236	—
생성물	(r)-4-Phenyl-2-oxazolidinone tetra n-butylammonium salt	HCID 86752286	—

반응 단계

To a stirred solution of (R)-4-phenyl-2-oxazolidinone (174 mg, 1.06 mmol) in THF (4 mL) at 0° C., add NaH (4.3 mg, 60% emulsion in oil, 0.106 mmol). Allow the temperature to rise to room temperature over 30 min., then add tetra n-butylammonium bromide (34 mg, 0.106 mmol) to the mixture and stir for another 30 min. to obtain (R)-4-phenyl-2-oxazolidinone tetra n-butylammonium salt.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US05728827
출처 데이터셋	uspto-grants-1998_03
ORD ID	ord-b9cf0611d38749c6a169a2037a147be6
출처 메모	uspto-grants-1998_03