Potassium Nitrate → HCID 14834673, 화합물

HRID 232644노트

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HRID 232644 반응식
[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[C:4]([F:9])[C:3]=1[CH3:10].[N+:11]([O-])([O-:13])=[O:12].[K+]>S(=O)(=O)(O)O>[F:1][C:2]1[C:7]([F:8])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[C:4]([F:9])[C:3]=1[CH3:10]

참가 물질

4

반응물 2

HCID 24434Potassium NitrateHCID 146512521,2,4-Trifluoro-3-methylbenzene

생성물 1

HCID 14834673HCID 14834673, 화합물수율 94.9%

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매2회

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온도
0 °C

실험 절차

To 2,3,6-trifluorotoluene (55 g) is added conc. sulfuric acid (366 ml) and the mixture is cooled to 0° C. Thereto a solution of potassium nitrate (44 g) in conc. sulfuric acid (120 ml) is added dropwise at below 10° C. and then the mixture is stirred for 15 minutes. The mixture is poured into ice-water, extracted with diethyl ether, and the extract is washed with water and dried. The solvent is distilled off to give 2,3,6-trifluoro-5-nitrotoluene (68.25 g), as yellow oil.

후처리

  1. extractionextracted with diethyl ether
  2. washthe extract is washed with water
  3. customdried
  4. distillationThe solvent is distilled off

출처 및 근거

ORD 기록
ord-ce0fde7983b64f6da4939107484cf7bf
출처 데이터셋
uspto-grants-1997_01
특허 번호
US05591744

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