Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thiophene-3-sulfonyl Chloride → N-(4-bromo-3-methyl-5-isoxazolyl)thiophene-3-sulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thiophene-3-sulfonyl Chloride | HCID 2776378 | — |
| 반응물 | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| 생성물 | N-(4-bromo-3-methyl-5-isoxazolyl)thiophene-3-sulfonamide | HCID 12146375 | 22% |
반응 단계
N-(4-Bromo-3-methyl-5-isoxazolyl)thiophene-3-sulfonamide was prepared in the same manner as described in Example 2 from thiophene-3-sulfonyl chloride with 5-amino-4-bromo-3-methylisoxazole in 22% yield. Purification by column chromatography using 10% MeOH/CHCl3 as eluent gave a pale brown oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05591761 |
| 출처 데이터셋 | uspto-grants-1997_01 |
| ORD ID | ord-5648f23a8a5649a0a6503bd53864150c |
| 출처 메모 | uspto-grants-1997_01 |