Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pregnenolone → Isopregnanolone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pregnenolone | HCID 8955 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Isopregnanolone | HCID 92787 | 96.2% |
반응 단계
A mixture of 3β-hydroxy-5-pregnen-20-one (980 mg, 316.5 g/m, 3.1 mmol) and 50 mg of 5% Pd/C in 50 mL of absolute ethyl alcohol was stirred under 1 atmosphere of hydrogen gas for 5 hours at room temperature. The reaction was filtered through a celite pad and the filtrate evaporated under reduced pressure to give 950 mg of 3β-hydroxy-5α-pregnan-20-one (96% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05591733 |
| 출처 데이터셋 | uspto-grants-1997_01 |
| ORD ID | ord-46dff4cc51f745f9a769e0a0f3cd1dbe |
| 출처 메모 | uspto-grants-1997_01 |