(4-Fluoro-2-methylphenyl)boronic acid → 4-(2,6-Difluoro-phenylamino)-6-(4-fluoro-2-methyl-phenyl)-2-methylsulfanyl-pyrimidine-5-carbaldehyde
반응식
[Cl:1][c:2]1[n:3][c:4]([S:19][CH3:20])[n:5][c:6]([NH:10][c:11]2[c:12]([F:18])[cH:13][cH:14][cH:15][c:16]2[F:17])[c:7]1[CH:8]=[O:9].[F:21][c:22]1[cH:23][c:24]([CH3:31])[c:25]([B:28]([OH:29])[OH:30])[cH:26][cH:27]1>>[c:2]1(-[c:25]2[c:24]([CH3:31])[cH:23][c:22]([F:21])[cH:27][cH:26]2)[n:3][c:4]([S:19][CH3:20])[n:5][c:6]([NH:10][c:11]2[c:12]([F:18])[cH:13][cH:14][cH:15][c:16]2[F:17])[c:7]1[CH:8]=[O:9]참가 물질
3
출처 및 근거
- ORD 기록
- ord-b7690213e2fd4aae852dec61feda6edd
- 출처 데이터셋
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
반응 노트
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