Chloride → 1-(6-Bromo-pyridin-2-ylmethyl)-3-(3-fluoro-4-methoxy-benzoyl)-7-trifluoromethyl-1H-[1,8]naphthyridin-4-one

HRID 2332098노트

반응식

[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:1][O:2][N:3]([C:4](=[O:5])[c:6]1[cH:7][n:8]([CH2:21][c:22]2[n:23][c:24]([Br:28])[cH:25][cH:26][cH:27]2)[c:9]2[n:10][c:11]([C:17]([F:18])([F:19])[F:20])[cH:12][cH:13][c:14]2[c:15]1=[O:16])[CH3:29].[Cl-:30].[F:31][c:32]1[cH:33][c:34]([Mg+:40])[cH:35][cH:36][c:37]1[O:38][CH3:39]>>[C:4](=[O:5])([c:6]1[cH:7][n:8]([CH2:21][c:22]2[n:23][c:24]([Br:28])[cH:25][cH:26][cH:27]2)[c:9]2[n:10][c:11]([C:17]([F:18])([F:19])[F:20])[cH:12][cH:13][c:14]2[c:15]1=[O:16])[c:34]1[cH:33][c:32]([F:31])[c:37]([O:38][CH3:39])[cH:36][cH:35]1