돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 233377생성일: 2026년 10월 25일

(S)-Benzyl 2-amino-3-(4-hydroxyphenyl)propanoate → N-[2-acetylthiomethyl-3-(4-hydroxyphenyl)-1-oxobutyl]tyrosine benzyl ester

https://huagongshe.com/reaction/233377

반응식

참여 물질

역할이름HCID투입량
반응물(S)-Benzyl 2-amino-3-(4-hydroxyphenyl)propanoateHCID 104541—
반응물2-Acetylthiomethyl-3-(4-hydroxyphenyl)butanoic acidHCID 18980788—
생성물N-[2-acetylthiomethyl-3-(4-hydroxyphenyl)-1-oxobutyl]tyrosine benzyl esterHCID 1007539878%

반응 단계

Using the procedure described in Example 60, but starting with 2-acetylthiomethyl-3-(4-hydroxyphenyl)butanoic acid and tyrosine benzyl ester, N-[2-acetylthiomethyl-3-(4-hydroxyphenyl)-1-oxobutyl]tyrosine benzyl ester is obtained in a 78% yield in the form of a white solid, having the following characteristics: Rf =0.16 [hexane/ethyl acetate (65:35 by volume)].

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05591891
출처 데이터셋uspto-grants-1997_01
ORD IDord-88813f320fae41578e2924c624159cdb
출처 메모uspto-grants-1997_01