Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
O-methylhydroxylammonium chloride → 2-Bromophenylglyoxylic Acid Methyl Ester-O-methyloxime
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | O-methylhydroxylammonium chloride | HCID 11639 | — |
| 반응물 | Methyl 2-(2-bromophenyl)-2-oxoacetate | HCID 10890094 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-Bromophenylglyoxylic Acid Methyl Ester-O-methyloxime | HCID 53728843 | — |
반응 단계
5.2 g (62 mmol) of 0-methylhydroxylamine hydrochloride is added to a solution of 10 g (41 mmol) of methyl 2-bromophenylglyoxylate in 30 ml of methanol, and the mixture is refluxed for 2 hours. The mixture is evaporated down, and the residue is taken up in ethyl acetate and washed with water. After drying and evaporating down, there remains 6.9 g (62%) of compound E.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05594020 |
| 출처 데이터셋 | uspto-grants-1997_01 |
| ORD ID | ord-d1c21c15754549efba5b4bfe8c4a63c4 |
| 출처 메모 | uspto-grants-1997_01 |