Dimethylformamide → Ethyl 2-(4-(4-(2-ethoxy-2-oxoethyl)phenyl)pyridin-2-yl)-2,2-difluoroacetate

반응식

[Br:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:12][cH:13]2)[cH:7]1.[Br:20][C:21]([C:22](=[O:23])[O:24][CH2:25][CH3:26])([F:27])[F:28].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[c:2]1([C:21]([C:22](=[O:23])[O:24][CH2:25][CH3:26])([F:27])[F:28])[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:12][cH:13]2)[cH:7]1

참가 물질

반응물 3

HCID 6228Dimethylformamide

HCID 69585Ethyl bromodifluoroacetate

HCID 58447951Ethyl 2-(4-(2-bromopyridin-4-yl)phenyl)acetate

생성물 1

HCID 58447939Ethyl 2-(4-(4-(2-ethoxy-2-oxoethyl)phenyl)pyridin-2-yl)-2,2-difluoroacetate

출처 및 근거

ORD 기록: ord-b5eae2149693498fabe3c974753a2108
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

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