Tetrahydrofuran → 4-Trifluoromethyl-3-[5-chloro-1-methyl-6-(4-trifluoromethyl-piperidin-1-yl)-1H-benzimidazol-2-ylamino]-benzylamine

반응식

[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH3:22])[c:7]([NH:9][c:10]3[cH:11][c:12]([C:13]#[N:14])[cH:15][cH:16][c:17]3[C:18]([F:19])([F:20])[F:21])[n:8]2)[cH:23][c:24]1[N:25]1[CH2:26][CH2:27][CH:28]([C:31]([F:32])([F:33])[F:34])[CH2:29][CH2:30]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH3:22])[c:7]([NH:9][c:10]3[cH:11][c:12]([CH2:13][NH2:14])[cH:15][cH:16][c:17]3[C:18]([F:19])([F:20])[F:21])[n:8]2)[cH:23][c:24]1[N:25]1[CH2:26][CH2:27][CH:28]([C:31]([F:32])([F:33])[F:34])[CH2:29][CH2:30]1

참가 물질

반응물 2

HCID 8028Tetrahydrofuran

HCID 866743443-(5-Chloro-1-methyl-6-(4-trifluoromethyl-piperidin-1-yl)-1H-benzo[d]imidazol-2-ylamino)-4-trifluoromethyl-benzonitrile

생성물 1

HCID 866743464-Trifluoromethyl-3-[5-chloro-1-methyl-6-(4-trifluoromethyl-piperidin-1-yl)-1H-benzimidazol-2-ylamino]-benzylamine

출처 및 근거

ORD 기록: ord-93e489e517b44b9e8ac581a9d7a9c74e
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

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