Sodium Azide → 2-Azido-1-(3,4-dihydroxyphenyl)ethanone
반응식
Cl[CH2:2][C:3]([C:5]1[CH:6]=[C:7]([OH:12])[C:8](=[CH:10][CH:11]=1)[OH:9])=[O:4].[N-:13]=[N+:14]=[N-:15].[Na+]>CN(C=O)C.C(OCC)(=O)C>[N:13]([CH2:2][C:3]([C:5]1[CH:6]=[C:7]([OH:12])[C:8](=[CH:10][CH:11]=1)[OH:9])=[O:4])=[N+:14]=[N-:15]참가 물질
5
실험 절차
To the solution of 4-chloroacetylcatechol (25 g) in DMF (200 ml) was added sodium azide (10.5 g), and the mixture was stirred at room temperature for 1 hour. The reaction mixture was diluted with ethyl acetate, washed with water and dried over anhydrous magnesium sulfate. After the solvent was evaporated, the solids thus obtained was washed with a solution of n-hexane:ether=5:1 to give 23.2 g of 4-azidoacetylcatechol (yield, 90%).
후처리
- washwashed with water
- dry with materialdried over anhydrous magnesium sulfate
- customAfter the solvent was evaporated
- customthe solids thus obtained
- washwas washed with a solution of n-hexane
출처 및 근거
- ORD 기록
- ord-afab536b3d874b7c898e921e9c48c510
- 출처 데이터셋
- uspto-grants-1997_01
- 특허 번호
- US05594004
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