Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chlorosulfonic acid → 2-Ethylbenzo[b]furan-3-sulfonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chlorosulfonic acid | HCID 24638 | — |
| 반응물 | Phosphorus pentachloride | HCID 24819 | — |
| 반응물 | 2-Ethylbenzofuran | HCID 76582 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Ethylbenzo[b]furan-3-sulfonyl chloride | HCID 22998408 | — |
반응 단계
2-Ethylbenzo[b]furan-3-sulfonyl chloride was prepared by the method of Example 82C with 2-ethylbenzo[b]furan (6.9 mmols, 1.0 g), chlorosulfonic acid (8.9 mmols, 0.6 ml) phosphorous oxychloride (21 mmols, 1.9 ml), phosphorous pentachloride (6.9 mmols, 1.4 g) and CH2Cl2 (10 ml). Flash chromatography (2% ethyl acetate/hexanes) provided 0.71 g (42%) of an orange solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05594021 |
| 출처 데이터셋 | uspto-grants-1997_01 |
| ORD ID | ord-6bbbd6bb37f840c49a7453d254ec080f |
| 출처 메모 | uspto-grants-1997_01 |