2-Bromo-5-fluorobenzonitrile → 4-Fluoro-3'-(7-methylimidazo[1,2-a]pyrimidin-3-yl)biphenyl-2-carbonitrile

반응식

[Br:26][c:27]1[c:28]([C:29]#[N:30])[cH:31][c:32]([F:35])[cH:33][cH:34]1.[CH3:1][c:2]1[n:3][c:4]2[n:5]([cH:6][cH:7]1)[c:8](-[c:11]1[cH:12][c:13]([B:17]3[O:18][C:19]([CH3:20])([CH3:21])[C:22]([CH3:23])([CH3:24])[O:25]3)[cH:14][cH:15][cH:16]1)[cH:9][n:10]2>>[CH3:1][c:2]1[n:3][c:4]2[n:5]([cH:6][cH:7]1)[c:8](-[c:11]1[cH:12][c:13](-[c:27]3[c:28]([C:29]#[N:30])[cH:31][c:32]([F:35])[cH:33][cH:34]3)[cH:14][cH:15][cH:16]1)[cH:9][n:10]2

참가 물질

반응물 2

HCID 936542-Bromo-5-fluorobenzonitrile

HCID 180012787-Methyl-3-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]imidazo[1,2-a]pyrimidine

생성물 1

HCID 101314624-Fluoro-3'-(7-methylimidazo[1,2-a]pyrimidin-3-yl)biphenyl-2-carbonitrile

출처 및 근거

ORD 기록: ord-a822256298ce47519944980132906eb4
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…