Phosphate → 2-Amino-5-tert-butyl-benzothiazole-6-thiol

HRID 23459

반응식

HRID 23459 반응식
[C:1]([C:5]1[C:6]([S:15]C#N)=[CH:7][C:8]2[S:12][C:11]([NH2:13])=[N:10][C:9]=2[CH:14]=1)([CH3:4])([CH3:3])[CH3:2].SC[C@H]([C@@H](CS)O)O.P([O-])([O-])([O-])=O>CCO>[NH2:13][C:11]1[S:12][C:8]2[CH:7]=[C:6]([SH:15])[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])=[CH:14][C:9]=2[N:10]=1

참가 물질

5

반응물 3

HCID 1061PhosphateHCID 446094D-1,4-DithiothreitolHCID 154738385-Tert-butyl-6-thiocyanato-benzothiazol-2-yl-amine

생성물 1

HCID 225728932-Amino-5-tert-butyl-benzothiazole-6-thiol

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The title compound was prepared according to General Method 14 using 5-tert-butyl-6-thiocyanato-benzothiazol-2-yl-amine (Example L-1; 8 g, 30 mmol), dithiothreitol (18.7 g, 121 mmol), EtOH (200 mL), and phosphate buffer (50 mL). MS (APCI): 239 (M+H).

출처 및 근거

ORD 기록
ord-cbb2200b505743f89d88f8471e6e0c7a
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06852711B2

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