Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → HCID 15279352, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 4-Chloro-5-methoxy-6-(methoxymethyl)pyrimidine | HCID 15279350 | — |
| 반응물 | HCID 15279351 | HCID 15279351 | — |
| 용매 | Toluene water | HCID 22272177 | — |
| 생성물 | HCID 15279352 | HCID 15279352 | — |
반응 단계
3.8 g (20 mmol) of 4-chloro-5-methoxy-6-methoxymethylpyrimidine (DE-A 4 116 089), 3.1 g (20 mmol) of 4-iso-butylidene-cyclohexylamine and 3.0 g (30 mmol) of triethylamine were stirred for 3 hours without solvent at 80°-90° C. After cooling, the mixture was taken up in water/toluene, and the organic phase was dried and evaporated on a rotary evaporator. Purification by chromatography (silica gel/ethyl acetate) gave 2.2 g (36% of theory) of a virtually colorless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05595992 |
| 출처 데이터셋 | uspto-grants-1997_01 |
| ORD ID | ord-8512c949f59e488294e44de880c15aaa |
| 출처 메모 | uspto-grants-1997_01 |