Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphate → 6-tert-Butyl-5-mercapto-2,3-dihydro-indole-1-carboxylic Acid Tert-Butyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphate | HCID 1061 | — |
| 반응물 | D-1,4-Dithiothreitol | HCID 446094 | — |
| 반응물 | 6-tert-Butyl-5-thiocyanato-2,3-dihydro-indole-1-carboxylic Acid Tert-Butyl Ester | HCID 54343849 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 6-tert-Butyl-5-mercapto-2,3-dihydro-indole-1-carboxylic Acid Tert-Butyl Ester | HCID 54077923 | — |
반응 단계
The title compound was prepared according to General Method 14 using 6-tert-butyl-5-thiocyanato-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester (prepared in Example KK; 2.0 g, 6.6 mmol), dithiothreitol (1.21 g, 7.9 mmol), EtOH (100 mL), and phosphate buffer (pH: 7.5, 10 mL). The crude product was used without any purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06852711B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-4785ced226c74426bde033d537ae8572 |
| 출처 메모 | uspto-grants-2005_02 |