Ammonium thiocyanate → HCID 22572976, 화합물
반응식
[C:1]([C:5]1[CH:6]=[CH:7][C:8]([N+:12]([O-:14])=[O:13])=[C:9]([NH2:11])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].[S-:15][C:16]#[N:17].[NH4+].BrBr>CO>[C:1]([C:5]1[C:6]([S:15][C:16]#[N:17])=[CH:7][C:8]([N+:12]([O-:14])=[O:13])=[C:9]([NH2:11])[CH:10]=1)([CH3:4])([CH3:2])[CH3:3]참가 물질
5
실험 절차
The title compound was prepared according to the General Method 13 using 5-tert-butyl-2-nitro-phenylamine (prepared in Example PP-2; 170 g, 876 mmol), ammonium thiocyanate (400 g, 5260 mmol), bromine (140 g, 876 mmol), and MeOH (500 mL). The crude reaction mixture was purified by flash silica gel chromatography (5%-50% EtOAc in hexanes as eluents). MS(APCI): 252 (M+H).
후처리
- customThe crude reaction mixture
- customwas purified by flash silica gel chromatography (5%-50% EtOAc in hexanes as eluents)
출처 및 근거
- ORD 기록
- ord-c3d67ade9bf444798c75e280e6f8169b
- 출처 데이터셋
- uspto-grants-2005_02
- 특허 번호
- US06852711B2
반응 노트
불러오는 중…