Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 3,5-Dichlorobenzyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3,5-Dichlorobenzylic alcohol | HCID 43236 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3,5-Dichlorobenzyl chloride | HCID 137880 | — |
반응 단계
A mixture of 3,5-dichlorobenzyl alcohol (Aldrich, 25 g) , thionyl chloride (100 ml) and DMF (0.5 ml) was stirred and refluxed for 4 hours. After cooling the mixture was concentrated in vacuo, the residue was taken up in ether, washed with saturated aqueous NaHCO3 and brine, dried (MgSO4) and concentrated in vacuo to give 3,5-dichlorobenzyl chloride as a light yellow solid, which was used without further purification, 28 g, mp. 32°-36° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05597827 |
| 출처 데이터셋 | uspto-grants-1997_01 |
| ORD ID | ord-0e68d73215e841639b2447213a833f42 |
| 출처 메모 | uspto-grants-1997_01 |