Trifluoroacetic acid → 4-(Carboxymethyloxy)-4'-cyano-biphenyl

HRID 234979

반응식

HRID 234979 반응식
C([O:5][C:6]([CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][CH:17]=2)=[CH:12][CH:11]=1)=[O:7])(C)(C)C.FC(F)(F)C(O)=O>C(Cl)Cl>[C:6]([CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][CH:17]=2)=[CH:14][CH:15]=1)([OH:7])=[O:5]

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 640094Tert-butyl [(4'-cyanobiphenyl-4-yl)oxy]acetate

생성물 1

HCID 432431004-(Carboxymethyloxy)-4'-cyano-biphenyl

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

32.9 g of 4-(tert.butyloxycarbonylmethyloxy)-4'-cyano-biphenyl dissolved in 250 ml of methylene chloride is mixed slowly with 137 ml of trifluoroacetic acid. After stirring for 3 hours, the reaction mixture is evaporated to dryness and the solid residue is triturated with water.

후처리

  1. customthe reaction mixture is evaporated to dryness
  2. customthe solid residue is triturated with water

출처 및 근거

ORD 기록
ord-2647d34b6ed04ee28679791fce90860a
출처 데이터셋
uspto-grants-1997_01
특허 번호
US05597825

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