1-Pyrrolidinamine → 2,10-Dihydro-10-(1-pyrrolidinyl)imidazo[2,1-b]quinazolin-5(3H)-one

HRID 2350856노트

반응식

HRID 2350856 반응식
F[C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[C:4]([N:6]1[CH2:10][CH2:9][N:8]=[C:7]1SC)=[O:5].[NH2:17][N:18]1[CH2:22][CH2:21][CH2:20][CH2:19]1>>[N:18]1([N:17]2[C:2]3[C:3](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:4](=[O:5])[N:6]3[CH2:10][CH2:9][N:8]=[C:7]23)[CH2:22][CH2:21][CH2:20][CH2:19]1

참가 물질

3

반응물 2

HCID 279461-PyrrolidinamineHCID 32369051-(2-Fluorobenzoyl)-2-methylthio-2-imidazoline

생성물 1

HCID 198473812,10-Dihydro-10-(1-pyrrolidinyl)imidazo[2,1-b]quinazolin-5(3H)-one

실험 절차

When the procedure of Example 2 is repeated using the product of Example 1 and N-aminopyrrolidine, the product obtained is 2,10-dihydro-10-(1-pyrrolidinyl)imidazo[2,1-b]quinazolin-4(3H)-one.

후처리

  1. customthe product obtained

출처 및 근거

ORD 기록
ord-a79e4c0bcf6d48bba92883d4c569f872
출처 데이터셋
uspto-grants-1989_10
특허 번호
US04871732

반응 노트

불러오는 중…