Thionyl Chloride → HCID 10543482, 화합물

HRID 235202노트

반응식

HRID 235202 반응식
O[CH:2]([C:10]1[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][CH2:18][C:19]([O:21][CH3:22])=[O:20])=[CH:12][CH:11]=1)[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.S(Cl)([Cl:25])=O>C1C=CC=CC=1>[Cl:25][CH:2]([C:10]1[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][CH2:18][C:19]([O:21][CH3:22])=[O:20])=[CH:12][CH:11]=1)[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 10756510HCID 10756510, 화합물

생성물 1

HCID 10543482HCID 10543482, 화합물

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

To a solution of 3.49 g of methyl 4-[4-(1-hydroxy-2-Phenylethyl)phenyl]butyrate in 17 ml of benzene, 1.10 ml of thionyl chloride was added dropwise under ice-cooling, and then stirring was continued at room temperature for 1.5 hours. The reaction solvent was removed under reduced pressure, and the residue was dissolved in ether. The ether layer was washed with water and dried, and then the solvent was removed under reduced pressure to yield 3.30 g of pale yellow oil.

후처리

  1. temperaturecooling
  2. customThe reaction solvent was removed under reduced pressure
  3. dissolutionthe residue was dissolved in ether
  4. washThe ether layer was washed with water
  5. customdried
  6. customthe solvent was removed under reduced pressure

출처 및 근거

ORD 기록
ord-a1981cf088524d3e906f77ee928e6c61
출처 데이터셋
uspto-grants-1997_01
특허 번호
US05597848

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