Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 2,3-dihydro-1H-pyrrolizine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 2,3-Dihydro-1h-pyrrolizine-1-carboxylic acid | HCID 12795105 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | Methyl 2,3-dihydro-1H-pyrrolizine-1-carboxylate | HCID 12795075 | — |
반응 단계
2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid is dissolved in methanol containing a small amount of concentrated hydrochloric acid. The resulting solution is heated to reflux, and then cooled. The title compound is isolated by rotary evaporation of the solvent under reduced pressure, and may be purified by chromatography on silica gel with hexane/ethyl acetate as eluent.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04874871 |
| 출처 데이터셋 | uspto-grants-1989_10 |
| ORD ID | ord-586d422b14554575a5537722250183b1 |
| 출처 메모 | uspto-grants-1989_10 |