Sulfuryl chloride → 4-n-Butoxy-3-chloro-1,1,1-trifluorobut-3-en-2-one
반응식
S(Cl)([Cl:4])(=O)=O.[CH2:6]([O:10][CH:11]=[CH:12][C:13](=[O:18])[C:14]([F:17])([F:16])[F:15])[CH2:7][CH2:8][CH3:9]>ClCCl>[CH2:6]([O:10][CH:11]=[C:12]([Cl:4])[C:13](=[O:18])[C:14]([F:16])([F:17])[F:15])[CH2:7][CH2:8][CH3:9]참가 물질
4
반응 조건
- 온도
- 0 °C
실험 절차
28.0 g (0.22 mole) of sulphuryl chloride in 60 ml of dichloromethane are added dropwise with stirring to 39.0 g (0.2 mole) of 4-n-butoxy-1,1,1-trifluoro-but-3-en-2-one in 200 ml of dichloromethane at 0° C. After stirring for 4 hours at 0° C., the solvent and unreacted sulphuryl chloride are distilled off and the residue is distilled slowly under reduced pressure. 42.5 g of pale yellow 4-n-butoxy-3-chloro-1,1,1-trifluorobut-3-en-2-one of boiling point 105°-106° C./12 mbar, nD20 =1.4484 are obtained.
후처리
- distillationthe solvent and unreacted sulphuryl chloride are distilled off
- distillationthe residue is distilled slowly under reduced pressure
출처 및 근거
- ORD 기록
- ord-0192ec466e904ec8b0dafeb7a17b6637
- 출처 데이터셋
- uspto-grants-1989_10
- 특허 번호
- US04876393
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