반응식
[CH2:1]([O:5][CH2:6][CH2:7][S:8][CH2:9][CH:10]1[CH2:12][O:11]1)[CH2:2][CH2:3][CH3:4].CC(C)([O-])C.[K+]>>[CH2:1]([O:5][CH2:6][CH2:7][S:8][CH:9]=[CH:10][CH2:12][OH:11])[CH2:2][CH2:3][CH3:4].[CH:1]([OH:5])=[CH:2][CH3:3]참가 물질
4
실험 절차
Following the procedure of Example 10, 2-butoxyethyltosylate (26.85 g, 98.7 mmol) and 3-mercapto-1,2-propanediol (10.68 g, 98.7 mmol) are reacted together to give 3-(2-butoxyethylthio)-1,2-propanediol, which diol (10.0 g, 52.5 mmol) is reacted with tosyl chloride (10.0 g) in pyridine. The tosylate (9.27 g, 25.6 mmol) is reacted with NaOH (1.02 g, 25.6 mmol) to give 2-(2-butoxyethylthiomethyl)oxirane. The oxirane (1.0 g, 5.26 mmol) and potassium t-butoxide (0.18 g, 1.58 mmol) are reacted together to give 3-(2-butoxyethylthio)-2-propenol, which propenol (4.72 g, 25.0 mmol) is reacted with acetic anhydride to give 3-(2-butoxyethylthio)-2-propenyl acetate.
출처 및 근거
- ORD 기록
- ord-7d88d35363c1442a9e293b6e08f663b4
- 출처 데이터셋
- uspto-grants-1989_10
- 특허 번호
- US04877899
연결된 노트
불러오는 중…