(Naphthalen-2-yl)boronic acid → HCID 57418691, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:8](I)=[CH:9][N:10]=2)[N:7]=1.[CH:12]1[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH:15]=[CH:14][C:13]=1B(O)O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:8]([C:14]3[CH:13]=[CH:12][C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH:15]=3)=[CH:9][N:10]=2)[N:7]=1

참가 물질

반응물 2

HCID 2734375(Naphthalen-2-yl)boronic acid

HCID 532498976-Chloro-3-iodoimidazo[1,2-b]pyridazine

생성물 1

HCID 57418691HCID 57418691, 화합물

실험 절차

1.03 g of 6-chloro-3-naphthalen-2-ylimidazo[1,2-b]pyridazine were prepared from 5 3.5 g (12.52 mmol) of 6-chloro-3-iodoimidazo[1,2-b]pyridazine (Example 1.2) and 2.37 g (13.78 mmol) of 2-naphthylboronic acid (CAS No. 32316-92-0) in analogy to Example 1.4.

출처 및 근거

ORD 기록: ord-c56d4fd9371446248c6e0feb4dfcd5d4
출처 데이터셋: uspto-grants-2010_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07750000B2

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